Grants & Funding

National Institutes of Health/National Institute of Allergy and Infectious Diseases

Published Date: June 29, 2010

Program Information

Program Name:

Martin Delaney Collaboratory: Towards an HIV-1 Cure (U19)

Program URL:

http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-10-009.html

Type of Scientists Funded:

Senior Scientist/Faculty

Program Description:

The National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Mental Health (NIMH), National Institutes of Health, encourage grant applications from institutions/organizations to address the problem of HIV-1 persistence in HIV-1-infected persons treated with suppressive antiretroviral drug regimens.

This funding opportunity announcement (FOA) will support research in four areas: (1) basic research to identify and characterize the cellular reservoirs of HIV-1 in treated individuals; (2) development of assays that are physiologically relevant and that comprise a spectrum of cell types that may harbor latent HIV-1 or permit viral replication in the presence of effective antiretroviral drug regimens; (3) screening of drug candidates that target latent/persistent HIV-1; and (4) development and initial testing of new agents or strategies aimed at the eradication of HIV-1.

The goal of this initiative is to expand the knowledge base on HIV-1 latency and persistence so that eradication strategies can be designed, developed, and evaluated. The application must include basic research and translational activities as essential components, and collaborators must include a private sector entity. This FOA will utilize the U19 award mechanism.

For this funding opportunity, the total amount of funds available from NIAID and NIMH is $8.5 million for fiscal year 2011. NIAID and NIMH expect to fund one or two awards.

Public Contact Information

Program Award Term and Application Process

• Award Term Fixed or Variable?    Variable
• Minimum Term     
• Maximum Term     
• Award Renewable?    No
• Does an individual or institution apply to the program?    Institution
• Is there a training component to this grant?   
• Is there an application deadline?    Yes
• Application deadline(s):
  10/04/2010,
  11/04/2010
• Deadline Comments   
  Letters of Intent Receipt Date: October 4, 2010 Application Receipt Dates: November 4, 2010

Program FUNDS

• Stipend Information:
  
  
• Annual stipend type:    Not Applicable
• 
  Research Allowance Information:
  
  
• Annual research allowance type:    Not Applicable
• 
  Indirect Costs (Institutional Funds) Information:
  
  
• Indirect costs type:    Not Applicable
• 
  Other Costs Information:
  
  
• Other Costs type:    Not Applicable

Program Eligibility Requirements

Research Areas:

Biology, Cell Biology, Chemistry, Disease-Specific Research: HIV/AIDS, Immunology, Social, Behavioral and Economic Sciences, Other (specify): Antiretroviral Drug

Application by invitation or nomination only?

No

Are awards limited to specific groups?

None provided

Must applicants be U.S. citizens and/or permanent residents?

U.S. geographic limits?

No

International geographic limits?

Institutional limits?

Yes

Details

The following organizations/institutions are eligible to apply: * Public/State Controlled Institutions of Higher Education * Private Institutions of Higher Education * Hispanic-serving Institutions * Historically Black Colleges and Universities (HBCUs) * Tribally Controlled Colleges and Universities (TCCUs) * Alaska Native and Native Hawaiian Serving Institutions * Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education) * Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education) * Small Businesses * For-Profit Organizations (Other than Small Businesses) * State Governments * Indian/Native American Tribal Governments (Federally Recognized) * Indian/Native American Tribally Designated Organizations * County Governments * City or Township Governments * Special District Governments * Independent School Districts * Public Housing Authorities/Indian Housing Authorities * U.S. Territory or Possession * Indian/Native American Tribal Governments (Other than Federally Recognized) * Regional Organizations * Other(s): o Eligible Agencies of the Federal Government o Faith-based or Community-based Organizations.

Non-domestic (non-U.S.) entities (Foreign Organizations) are not eligible to serve as primary applicants for this FOA. However, foreign components may submit a research project or core within a domestic application, under this FOA. The instructions for submission of research projects or cores are located in the supplemental instructions (Section IV.6, Other Submission Requirements).

Non-research activity allowed for postdoctoral and junior faculty awards?

If yes, specify at least one of the following: percentage time and activities allowed

• Other eligibility requirements:   
  Multiple PDs/PIs may be designated on the primary U19 application. However, only one Project Leader (PL) or Core Leader (CL) may be designated for each project or core, respectively, for multi-project U19 applications.
  
  A PD/PI, or PD/PI on a multi-PI application, or U19 PL may serve as a collaborator for another application provided there is no scientific overlap with the application submitted by the PD/PI, multi-PD/PI, or U19 PL. However, an investigator may only be a PD/PI, multi-PD/PI, or U19 PL on one application.
  
  The PD/PI must devote at least 2.4 person months effort to the project (this includes a minimum 0.6 person months effort to the management and operations activities).
  
  Applicants may submit more than one application, provided they are scientifically distinct. Resubmission applications are not permitted in response to this FOA. Renewal applications are not permitted in response to this FOA.

Program competition information

• Number of Applicants in Most Recent Competition Year:   
• Number of Awards in Most Recent Competition Year:   
• Institutional Award Rates   

  Category	# Applicants	# Awards
  Institutional Awards

• Awardee's subsequent careers/accomplishments tracked after end of term?   
  
• Total dollars awarded in the most recent competition year